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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Synthesis, Structure–Activity Relationship, and Selective Antitumor Activity | Journal of Medicinal Chemistry
Representative IC50 values for enzyme inhibition. | Download Table
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site | Science Advances
Principles of Kinase Allosteric Inhibition and Pocket Validation | Journal of Medicinal Chemistry
GW27-e0919 CYP4F2 polymorphism and bleeding complications in Chinese patients on warfarin therapy | Journal of the American College of Cardiology
Segregating Top-Down Selective Attention from Response Inhibition in a Spatial Cueing Go/NoGo Task: An ERP and Source Localization Study | Scientific Reports
Inhibition of NADPH Oxidase Attenuates Vasospasm After Experimental Subarachnoid Hemorrhage in Rats | Stroke
Frontiers | Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations
Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs | Nature Communications
Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands | ACS Chemical Biology
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir | Science
Distinct mechanisms for TMPRSS2 expression explain organ-specific inhibition of SARS-CoV-2 infection by enzalutamide | Nature Communications
PDF) Self-transcendence through self-inhibition?: God primes reduce self-accessibility.
GW26-e4658 Study on the Molecular Genetic between Hypertrophic Cardiomyopathy and FKBP12.6 | Journal of the American College of Cardiology
PDF) Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
Selective inhibition of cullin 3 neddylation through covalent targeting DCN1 protects mice from acetaminophen-induced liver toxicity | Nature Communications
Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5 | Journal of the American Chemical Society
Cardamonin suppresses pro-tumor function of macrophages by decreasing M2 polarization on ovarian cancer cells via mTOR inhibition: Molecular Therapy - Oncolytics
PDF) BRD4 Inhibition Protects Against Acute Pancreatitis Through Restoring Impaired Autophagic Flux
Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors | Journal of Medicinal Chemistry
GW26-e1234 A prescription of Jiashen reduces postinfarct left ventricular remodeling via inhibition of TGF-β/Smads signaling pathway | Journal of the American College of Cardiology
Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound | Cell Death & Disease
Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization | Journal of the American Chemical Society